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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
Podophyllotoxin [518-28-5]
Catalog number:
AG-CN2-0049-M100
Brand:
AdipoGen Life Sciences
Packing:
100 mg
Other sizes:
Other size available
Price:
€ 40.00
Expected delivery time:
7 days
Quantity:
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General
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References
Chemical Structure
Chemical Structure...
Chemical Structure
Chemical Structure
Product specifications for - Podophyllotoxin [518-28-5]
Overview:
Product group:
Chemicals
Category:
Other
CAS No.:
518-28-5
Properties:
Purity:
>98%
Molecular Formula:
C22H22O8
Molecular weight:
414.4
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352200
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Chemical. CAS: 518-28-5. Formula: C22H22O8. MW: 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic. - Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.
Safety information:
ADR klasse:
6.1
UN Number:
UN 2811
MSDS:
MSDS
Hazard information:
Danger, Excepted quantity
Additional information:
Synonyms:
AG-CN2-0049-M100
VP16-213 and podophyllotoxin. A study on the relationship between chemical structure and biological activity: J.D. Loike; Cancer Chemother. Pharmacol. 7, 103 (1982)
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Antitumor agents. I. DNA topoisomerase II inhibitory activity and the structural relationship of podophyllotoxin derivatives as antitumor agents: T. Terada, et al.; Chem. Pharmacol. Bull. (Tokyo) 40, 2720 (1992)
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Antineoplastic and antiviral activities of podophyllotoxin related lignans: M. Gordaliza, et al.; Arch. Pharmacol. 327, 175 (1994)
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Podophyllotoxin: C. Canel, et al.; Phytochemistry 54, 115 (2000) (Review)
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Antitumor properties of podophyllotoxin and related compounds: M. Gordaliza, et al.; Curr. Pharm. Des. 6, 1811 (2000) (Review)
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Drugs that inhibit tubulin polymerization: the particular case of podophyllotoxin and analogues: S. Desbene & S. Giorgi-Renault; Curr. Med. Chem. Anticancer Agents 2, 71 (2002) (Review)
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Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents: Y. You; Curr. Pharm. Des. 11, 1695 (2005) (Review)
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Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile: J.T. Hartmann & H.P. Lipp; Drug Saf. 29, 209 (2006) (Review)
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An evidence-based review of medical and surgical treatments of genital warts: N. Scheinfeld & D.S. Lehman; Dermatol. Online J. 12, 5 (2006)
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