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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
Pseudolaric acid B [82508-31-4]
Catalog number:
AG-CN2-0083-C100
Brand:
AdipoGen Life Sciences
Packing:
100 ug
Other sizes:
Other size available
Price:
€ 30.00
Expected delivery time:
7 days
Quantity:
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Chemical Structure
Chemical Structure...
Chemical Structure
Chemical Structure
Product specifications for - Pseudolaric acid B [82508-31-4]
Overview:
Product group:
Chemicals
Category:
Other
CAS No.:
82508-31-4
Properties:
Purity:
>98%
Molecular Formula:
C23H28O8
Molecular weight:
432.5
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352200
Storage instructions:
2-¦C to 8-¦C
Scientific information:
Scientific info:
Antifungal and antifertility compound. Antitumor compound. PPARalpha signaling agonist. Angiogenesis inhibitor. Apoptosis and autophagy inducer. Microtubule-destabilizing agent. Anti-inflammatory. Inhibits NF-kappaB and p38 signaling. Immunosuppressive. - Chemical. CAS: 82508-31-4. Formula: C23H28O8. MW: 432.5. Isolated from Pseudolarix kaempferi. Antifungal and antifertility compound. Antitumor compound. PPARalpha signaling agonist. Angiogenesis inhibitor. Apoptosis and autophagy inducer. Microtubule-destabilizing agent. Anti-inflammatory. Inhibits NF-kappaB and p38 signaling. Immunosuppressive.
Safety information:
ADR klasse:
6.1
UN Number:
UN 2811
MSDS:
MSDS
Hazard information:
Danger, Excepted quantity
Additional information:
Synonyms:
AG-CN2-0083-C100
Pseudolaric Acids from Pseudolarix kaempferi: B.N. Zhou, et al.; Planta Med. 47, 35 (1983)
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The cytotoxic principles of Pseudolarix kaempferi: pseudolaric acid-A and -B and related derivatives: D.J. Pan, et al.; Planta Med. 56, 383 (1990)
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Antifungal evaluation of pseudolaric acid B, a major constituent of Pseudolarix kaempferi: E. Li, et al.; J. Nat. Prod. 58, 57 (1995)
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Pseudolaric acid analogs as a new class of peroxisome proliferator-activated receptor agonists: M.S. Jardat, et al.; Planta Med. 68, 667 (2002)
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Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect: W.F. Tan, et al.; Eur. J. Pharmacol. 499, 219 (2004)
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Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation: M.H. Li, et al.; Clin. Cancer Res. 10, 8266 (2004)
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Pseudolaric acid B induces apoptosis through p53 and Bax/Bcl-2 pathways in human melanoma A375-S2 cells: X.F. Gong, et al.; Arch. Pharm. Res. 28, 68 (2005)
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Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo: V.K. Wong, et al.; Clin. Cancer Res. 11, 6002 (2005)
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Effect of pseudolaric acid B on gastric cancer cells: inhibition of proliferation and induction of apoptosis: K.S. Li, et al.; World J. Gastroenterol. 11, 7555 (2005)
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Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin: Y.G. Tong, et al.; Mol. Pharmacol. 69, 1226 (2006)
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