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SN-38 [86639-52-3]

Research Use Only
HY-13704
MedChem Express
CAS Number86639-52-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.89
Molecular Weight392.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SN-38 [86639-52-3]
  • Delivery Days Customer
    10
  • CAS Number
    86639-52-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C22H20N2O5
  • Molecular Weight
    392.40
  • Scientific Description
    SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 microM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254)[1][2][3][4][5].
  • SMILES
    O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200