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Tacrolimus (FK506) [104987-11-3]

S5003
Selleck Chemicals
CAS Number104987-11-3
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Tacrolimus (FK506) [104987-11-3]
  • Delivery Days Customer
    9
  • CAS Number
    104987-11-3
  • Certification
    Research Use Only
  • Scientific Description
    Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.
  • UNSPSC
    12352200

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