Y-27632
HY-10071
CAS Number146986-50-7
Product group Chemicals
Estimated Purity99.91
Molecular Weight247.342
Overview
- SupplierMedChem Express
- Product NameY-27632 [146986-50-7]
- Delivery Days Customer10
- CAS Number146986-50-7
- CertificationResearch Use Only
- Estimated Purity99.91
- Molecular FormulaC14H21N3O
- Molecular Weight247.342
- Scientific DescriptionY-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II , with K i s of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation [1] [2] [3] [4] [5] [6] [7] .
- SMILESO=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
- Storage Instruction-20°C
- UNSPSC12352200