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CHIKV-IN-2

T9394
TargetMol Chemicals
CAS Number2361289-44-1
Product group Chemicals
Molecular Weight362.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CHIKV-IN-2
  • Delivery Days Customer
    4
  • CAS Number
    2361289-44-1
  • Category Supplier
    Chemical
  • Chemical Name
    CHIKV-IN-2
  • Molecular Formula
    C23H26N2O2
  • Molecular Weight
    362.46
  • Scientific Description
    CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effective Chikungunya virus (CHIKV) inhibitor, demonstrating significant cellular antiviral activity (EC90=270 nM) and enhanced liver microsomal stability[1].
  • Shelf life instruction
    3 years
  • SMILES
    C(NC1=CC=C(C(C#N)(C)C)C=C1)(=O)C2=C(OC)C=C3C(=C2)CCCCC3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Ahmed SK, et, al. Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors. J Med Chem. 2021 Apr 22;64(8):4762-4786.
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