CHIR-98014

Biorbyt

CHIR-98014 [252935-94-7]

16

252935-94-7

Research Use Only

C20H17CL2N9O2

486.3141

CHIR-98014 is a potent GSK-3alpha/beta inhibitor with IC50 of 0.65 nM/0.58 nM, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.

ClC1C([H])=C(C([H])=C([H])C=1C1C(=C([H])N=C(N=1)N([H])C([H])([H])C([H])([H])N([H])C1C([H])=C([H])C(=C(N([H])[H])N=1)[N+](=O)[O-])N1C([H])=NC([H])=C1[H])Cl

12352200