CHIT1 Polyclonal Antibody

Reddot Biotech

CHIT1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

CHIT1

chitinase 1

CHI3; CHIT; CHITD; chitinase 1 (chitotriosidase); chitotriosidase-1; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase

Rabbit

IgG

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Human, Mouse

-20°C

12352203