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Chk2 Inhibitor II (BML-277) [516480-79-8]

Research Use Only
S8632
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Chk2 Inhibitor II (BML-277) [516480-79-8]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Chk2 Inhibitor II (BML-277) is an ATP-competitive inhibitor of Chk2 with IC50 of 15 nM. It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases. Chk2 Inhibitor II (BML-277) dose dependently protects human CD4(+) and CD8(+) T-cells from apoptosis due to ionizing radiation.
  • UNSPSC
    12352200