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Chlorpromazine (hydrochloride)

HY-B0407A
MedChem Express
CAS Number69-09-0
Product group Chemicals
Estimated Purity99.90
Molecular Weight355.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Chlorpromazine (hydrochloride)
  • Delivery Days Customer
    9
  • CAS Number
    69-09-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.90
  • Molecular Formula
    C17H20Cl2N2S
  • Molecular Weight
    355.33
  • Scientific Description
    Chlorpromazine hydrochloride is an orally active, blood-brain barrier-transparent antipsychotic agent that effectively antagonises D2 dopamine receptors and 5-HT 2A , which is widely used in schizophrenia and other psychiatric disorders. Chlorpromazine hydrochloride exerts anti-cancer activity through a variety of pathways, including anti-proliferation, induction of autophagy and cycle arrest (G2-M phase), inhibition of cytochrome c oxidase ( CcO ), inhibition of tumour growth and metastasis, and inhibition of tumour immune escape. Chlorpromazine hydrochloride also blocks hNa v 1.7 channels ( IC 50 =25.9 microM; concentration-dependent) and HERG potassium channels ( IC 50 =21.6 microM), which has potential for analgesic and cardiac arrhythmic studies. Chlorpromazine hydrochloride also can inhibit clathrin-mediated endocytosis [1] [2] [3] [4] [5] .
  • SMILES
    CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=C(Cl)C=C13.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200