CHMFL-ABL-053

MedChem Express

CHMFL-ABL-053

10

Research Use Only

C28H26F3N7O2

549.55

CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available BCR-ABL , SRC and p38 kinase inhibitor with IC 50 values of 70, 90 and 62 nM against ABL1, SRC and p38, respectively [1] .

O=C(C1=CN=C(NC2=CC=C(C)C(N)=C2)N=C1NC)NC3=CC(NC(C4=CC=CC(C(F)(F)F)=C4)=O)=CC=C3C

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