CHMFL-FLT3-122

MedChem Express

CHMFL-FLT3-122 [1839150-56-9]

5

1839150-56-9

Research Use Only

98.47

C26H29N7O2

471.55

CHMFL-FLT3-122 is a potent, selective and orally active FLT3 kinase with an IC 50 of 40 nM. CHMFL-FLT3-122 shows selectivity for FLT3 over BTK (IC 50 of 421 nM) and c-KIT (IC 50 of 559 nM) kinases. CHMFL-FLT3-122 induces apoptosis by arresting the cell cycle into the G0/G1 phase [1] .

NC1=C2C(N([C@H]3CN(CCC3)C(CN(C)C)=O)N=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1

-20°C,2°C to 8°C

12352200