CHMFL-PI4K-127 [2377604-81-2]

MedChem Express

CHMFL-PI4K-127 [2377604-81-2]

10

2377604-81-2

Research Use Only

99.94

C18H15ClN4O3S

402.85

CHMFL-PI4K-127 (compound 15g) is an orally active, potent and high selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor, with an IC50 of 0.9 nM. CHMFL-PI4K-127 exhibits potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM. CHMFL-PI4K-127 shows antimalaria efficacy[1].

O=C(C1=CN=CC(C2=CC(NS(=O)(C3=CC=CC=C3)=O)=C(Cl)N=C2)=C1)NC

-20°C,2°C to 8°C

12131703