ChoKalpha inhibitor-4

MedChem Express

ChoKalpha inhibitor-4

10

Research Use Only

C54H68Br2N4S4

1061.21

ChoKalpha inhibitor-4 is a bioisosteric inhibitor of HChoK alpha1 (IC50=0.66 microM), with inhibitory and antiproliferative effect on cancer cells. ChoKalpha inhibitor-4 induces apoptosis via mitochondrial pathway, and reduces anti-apoptotic proteins expression[1].

C=CCCCCN(C1=CC=[N+](C2=C1C=CS2)CC3=CC=C(C=C3)SCCSC4=CC=C(C=C4)C[N+]5=CC=C(C6=C5SC=C6)N(CCCCC=C)CCCCC=C)CCCCC=C.[Br-].[Br-]

12131703