Cholesterol (Excipient)

MedChem Express

Cholesterol (Excipient) [57-88-5]

5

57-88-5

Research Use Only

99.90

C27H46O

386.65

Cholesterol Excipient is a component of the cell membrane and a precursor of some hormones, vitamin D and bile acid, with oral activity. Cholesterol Excipient is a drug delivery carrier based on the lipid environment of the cell membrane. Due to its amphiphilicity, good biocompatibility and biodegradability, it can be used as an excipient in drug preparations. Cholesterol Excipient can self-assemble into delivery systems such as micelles, nanoparticles, and liposomes, and achieve controlled drug release by regulating membrane fluidity or responding to the microenvironment. It has the characteristics of high drug loading efficiency and good biocompatibility. Cholesterol Excipient is mainly used for research in the fields of targeted delivery of anticancer, antibacterial, antiviral drugs and treatment of skin diseases. Cholesterol itself is also an endogenous regulator involved in the cleavage of amyloid precursor protein (APP) mediated by beta-secretase and intestinal absorption, as well as an endogenous estrogen-related receptor alpha (ERRalpha) agonist. Cholesterol affects the subcellular localization of APP processing enzymes by regulating the cell membrane lipid environment, which can promote the production of beta-amyloid protein and its adsorption and removal by probiotics. It is used to study the pathogenesis of Alzheimers disease (AD) and the cholesterol-lowering function of probiotics[1][2][3][4][5].

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](CCCC(C)C)C

-20°C

12352200