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Chemical Structure
Chemical Structure
Chemical Structure

Cholesteryl hemisuccinate [1510-21-0]

Research Use Only
CDX-C0828
Chemodex
CAS Number1510-21-0
Product group Chemicals
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Overview

  • Supplier
    Chemodex
  • Product Name
    Cholesteryl hemisuccinate
  • Delivery Days Customer
    10
  • CAS Number
    1510-21-0
  • Certification
    Research Use Only
  • Scientific Description
    Chemical. CAS: 1510-21-0. Formula: C31H50O4. MW: 486.73. Soluble in chloroform (10mg/ml), DMSO or ethanol (both 1mg/ml). Cholesteryl hemisuccinate (CHEMS) is a cholesterol ester. It is formed by esterifying cholesterol with succinic acid. The chemical structure comprises a cholesterol molecule attached to a succinic acid moiety. It possesses both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, making it useful as a surfactant. CHEMS can form lyotropic liquid crystals, which are important in the formation of liposomes and other nanoparticle drug delivery systems. CHEMS acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. CHEMS is commonly used in the formulation of liposomes and other lipid-based drug delivery systems. These systems can encapsulate drugs, enhancing their stability, bioavailability, and controlled release. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts. In addition is used in the study of membrane proteins and the biophysical properties of cell membranes. CHEMS has also been described to have anticancer activity. - Cholesteryl hemisuccinate (CHEMS) is a cholesterol ester. It is formed by esterifying cholesterol with succinic acid. The chemical structure comprises a cholesterol molecule attached to a succinic acid moiety. It possesses both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, making it useful as a surfactant. CHEMS can form lyotropic liquid crystals, which are important in the formation of liposomes and other nanoparticle drug delivery systems. CHEMS acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes. CHEMS is commonly used in the formulation of liposomes and other lipid-based drug delivery systems. These systems can encapsulate drugs, enhancing their stability, bioavailability, and controlled release. It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts. In addition is used in the study of membrane proteins and the biophysical properties of cell membranes. CHEMS has also been described to have anticancer activity.
  • Storage Instruction
    RT
  • UNSPSC
    12352200