Western Blot analysis of Mouse heart tissue using CHRNA7 Polyclonal Antibody at dilution of 1:700
Western Blot analysis of Mouse heart tissue using CHRNA7 Polyclonal Antibody at dilution of 1:700
CHRFAM7A Polyclonal Antibody
E-AB-12583
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCHRFAM7A Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThe nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
- UNSPSC12352203