CHS-111

TargetMol Chemicals

CHS-111

65

886755-63-1

Chemical

CHS-111

C21H18N2O

314.38

CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2uM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homology (Rho) A, and reduces the membrane recruitment of RhoA in fMLP-stimulated cells.

3 years

C(N1C(=C2C(=N1)C=CC=C2)C3=CC=C(CO)C=C3)C4=CC=CC=C4

-20°

12352200