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CHS-828 (nicotinate)

HY-10079A
MedChem Express
Molecular Weight494.97
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CHS-828 (nicotinate)
  • Delivery Days Customer
    9
  • Molecular Formula
    C25H27ClN6O3
  • Molecular Weight
    494.97
  • Scientific Description
    CHS-828 nicotinate is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) , with an IC 50 less than 25 nM. CHS-828 nicotinate (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD + and exhibits a potent anticancer activity [1] .
  • SMILES
    N#CN/C(NCCCCCCOC1=CC=C(C=C1)Cl)=N\C2=CC=NC=C2.O=C(C3=CC=CN=C3)O
  • UNSPSC
    12352200