CHST2 Antibody

Cusabio

CHST2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

CHST2

carbohydrate sulfotransferase 2

C6ST; carbohydrate (chondroitin 6/keratan) sulfotransferase 2; carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2; carbohydrate sulfotransferase 2; epididymis secretory protein Li 75; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2; glcNAc6ST-1; Gn6ST-1; GST2; GST-2; HEL-S-75; N-acetylglucosamine 6-O-sulfotransferase 1

Rabbit

IgG

Carbohydrate sulfotransferase 2

Sulfotransferase that utilizes 3-phospho-5-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains. Uchimura K., J. Biochem. 124:670-678(1998). Li X., Genomics 55:345-347(1999). Sakaguchi H., Biochim. Biophys. Acta 1523:269-276(2000).

Human

-20°C or -80°C

12352203