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CI-966 (hydrochloride)

HY-103534
MedChem Express
CAS Number110283-66-4
Product group Chemicals
Estimated Purity99.0
Molecular Weight509.87
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CI-966 (hydrochloride)
  • Delivery Days Customer
    9
  • CAS Number
    110283-66-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C23H22ClF6NO3
  • Molecular Weight
    509.87
  • Scientific Description
    CI-966 hydrochloride is a potent, selective, orally active and brain-penetrant inhibitor of the GABA transporter GAT-1 , with IC 50 s of 0.26 microM and 1.2 microM for hGAT-1 , rGAT-1 , respectively. CI-966 hydrochloride shows more than 200-fold selectivity over GAT-2, GAT-3, and BGT-3. CI-966 hydrochloride exhibits anticonvulsant and neuroprotective activities [1] [2] [3] .
  • SMILES
    O=C(C1=CCCN(CCOC(C2=CC=C(C(F)(F)F)C=C2)C3=CC=C(C(F)(F)F)C=C3)C1)O.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200