CIAC001 [2649154-82-3]

TargetMol Chemicals

CIAC001 [2649154-82-3]

86

Chemical

Research Use Only

CIAC001

C20H25N3O2

339.43

CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties. It effectively suppresses LPS-induced production of proinflammatory nitric oxide (NO) and provides protection to immunologically active BV-2 cells with an IC50 value of 2.5 microM. Additionally, CIAC001 demonstrates anti-neuroinflammation effects in mouse models and attenuates chronic morphine-induced addiction [1].

3 years

C(C)(=C)[C@H]1[C@@H](C=C(C)CC1)C2=C(O)C=C(C(C)N3N=CC=N3)C=C2O

-20°C

12352200