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Cilofexor (tromethamine)

HY-109083A
MedChem Express
CAS Number2253764-93-9
Product group Chemicals
Molecular Weight707.99
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Cilofexor (tromethamine)
  • Delivery Days Customer
    9
  • CAS Number
    2253764-93-9
  • Certification
    Research Use Only
  • Molecular Formula
    C32H33Cl3N4O8
  • Molecular Weight
    707.99
  • Scientific Description
    Cilofexor tromethamine (GS-9674 tromethamine) is a nonsteroidal farnesene oxide receptor agonist with activity in improving markers of cholestasis and liver injury. Cilofexor tromethamine was shown to be well tolerated in patients without cirrhosis and resulted in significant improvements in liver biochemical parameters and cholestatic markers. Cilofexor tromethamine offers a potential inhibitory option for the management of primary sclerosing cholangitis [1] .
  • SMILES
    O=C(C1=CC(N2CC(C3=CC=C(C=C3Cl)OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)(C2)O)=NC=C1)O.OCC(CO)(CO)N
  • UNSPSC
    12352200