Cinanserin (hydrochloride)

MedChem Express

Cinanserin (hydrochloride) [54-84-2]

10

54-84-2

99.48

C20H25ClN2OS

376.94

Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT 2 receptor antagonist with a K i of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT 2 than for the 5-HT 1 receptor ( K i of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro [1] [2] [3] .

O=C(NC1=CC=CC=C1SCCCN(C)C)/C=C/C2=CC=CC=C2.[H]Cl

2°C to 8°C

12352200