cis-11,14-Eicosadienoic acid methyl ester

MedChem Express

cis-11,14-Eicosadienoic acid methyl ester [61012-46-2]

5

61012-46-2

Research Use Only

C21H38O2

322.53

cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the omega-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5-monophosphate dehydrogenase (Ki=3.1 microM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 microM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

CCCCC/C=C\C/C=C\CCCCCCCCCC(OC)=O

12352200