cis-SU4312

MedChem Express

cis-SU4312

5

Research Use Only

C17H16N2O

264.32

cis-SU4312 ((Z)-SU4312) inhibits PDGFR and FLK-1 with IC 50 s of 19.4 and 0.8 microM, respectively. cis-SU4312 inhibits PDGFR , FLK-1, EGFR, HER-2, and IGF-1R with IC 50 s of 24.2, 5.2, 18.5, 16.9 and 10.0 microM, respectively. cis-SU4312 can cross blood brain barrier [1] .

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N(C)C)C=C3

12352200