CITED4 Polyclonal Antibody
RD219707A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCITED4
Overview
- SupplierReddot Biotech
- Product NameCITED4 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.9 mg/ml
- ConjugateUnconjugated
- Gene ID163732
- Target nameCITED4
- Target descriptionCbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4
- Target synonymscbp/p300-interacting transactivator 4; MRG-2; MSG1-related protein 2; transcriptional co-activator 4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203