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cjoc42 [2171519-89-2]

Research Use Only
T27029
TargetMol Chemicals
Molecular Weight415.46
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    cjoc42 [2171519-89-2]
  • Delivery Days Customer
    9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    cjoc42
  • Molecular Formula
    C20H21N3O5S
  • Molecular Weight
    415.46
  • Scientific Description
    Cjoc42 is an inhibitor of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the development of many cancer types. cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin, and it restores p53-dependent transcription and sensitivity to DNA damage
  • Shelf life instruction
    3 years
  • SMILES
    COC(=O)c1ccc(cc1)-n1cc(CCCOS(=O)(=O)c2ccc(C)cc2)nn1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Chattopadhyay A, et al. Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell. Sci Rep. 2016;6:23732.
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