CKI-7 (free base)

MedChem Express

CKI-7 (free base) [120615-25-0]

9

120615-25-0

Research Use Only

99.34

C11H12ClN3O2S

285.75

CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 microM and a Ki of 8.5 microM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases[1][2][3][4].

O=S(C1=CC=C(Cl)C2=C1C=NC=C2)(NCCN)=O

-20°C,2°C to 8°C

12352200