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CgoaEWY7KiWEJkQgAAAAAFTmnz8664.png
CgoaEWY7KiWEJkQgAAAAAFTmnz8664.png
CgoaEWY7KiWEJkQgAAAAAFTmnz8664.png

CKI-7 free base

Research Use Only
T10829
TargetMol Chemicals
CAS Number120615-25-0
Product group Chemicals
Molecular Weight285.75
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Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CKI-7 free base
  • Delivery Days Customer
    14
  • CAS Number
    120615-25-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CKI-7 free base
  • Molecular Formula
    C11H12ClN3O2S
  • Molecular Weight
    285.75
  • Scientific Description
    CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 uM; Ki: 8.5 uM) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
  • Shelf life instruction
    3 years
  • SMILES
    S(NCCN)(=O)(=O)C=1C2=C(C(Cl)=CC1)C=CN=C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Osakada F, et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci. 2009 Sep 1;122(Pt 17):3169-79.
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