CKMT2 Antibody

Cusabio

CKMT2 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Liquid

CKMT2

creatine kinase, mitochondrial 2

basic-type mitochondrial creatine kinase; creatine kinase S-type, mitochondrial; creatine kinase, mitochondrial 2 (sarcomeric); mib-CK; sarcomeric mitochondrial creatine kinase; SMTCK; S-MtCK

Rabbit

IgG

Creatine kinase S-type, mitochondrial

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

Human

-20°C or -80°C

12352203