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Immunohistochemistry (IHC) analyzes of Claudin-5 pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Immunohistochemistry (IHC) analyzes of Claudin-5 pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Immunohistochemistry (IHC) analyzes of Claudin-5 pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Claudin 5 antibody

Research Use Only
GTX49370
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rat
TargetCLDN5
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Overview

  • Supplier
    GeneTex
  • Product Name
    Claudin 5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000, IHC: 1:50-1:200, ICC/IF: 1:50-1:200
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7122
  • Target name
    CLDN5
  • Target description
    claudin 5
  • Target synonyms
    AWAL; BEC1; claudin-5; CPETRL1; TMDVCF; TMVCF; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00501
  • Protein Name
    Claudin-5
  • Scientific Description
    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
  • Reactivity
    Human, Monkey, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction. Shen S et al., 2022 Mar, Bioengineered
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  • Characterization of a Primate Blood-Brain Barrier Co-Culture Model Prepared from Primary Brain Endothelial Cells, Pericytes and Astrocytes. Watanabe D et al., 2021 Sep 16, Pharmaceutics
    Read more
  • IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease. Wang M et al., 2020 Aug 28, Aging (Albany NY)
    Read more
  • Basic Fibroblast Growth Factor (bFGF) Protects the Blood-Brain Barrier by Binding of FGFR1 and Activating the ERK Signaling Pathway After Intra-Abdominal Hypertension and Traumatic Brain Injury. Chen P et al., 2020 Feb 9, Med Sci Monit
    Read more
  • Basic Fibroblast Growth Factor Reduces Permeability and Apoptosis of Human Brain Microvascular Endothelial Cells in Response to Oxygen and Glucose Deprivation Followed by Reoxygenation via the Fibroblast Growth Factor Receptor 1 (FGFR1)/ERK Pathway. Chen P et al., 2019 Sep 25, Med Sci Monit
    Read more