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ICC/IF analysis of formalin-fixed HeLa cells using GTX55139 CLCN7 antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
ICC/IF analysis of formalin-fixed HeLa cells using GTX55139 CLCN7 antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes
ICC/IF analysis of formalin-fixed HeLa cells using GTX55139 CLCN7 antibody. Red : Primary antibody Blue : DAPI Permeabilization : 0.1% Triton X-100 in TBS for 5-10 minutes

CLCN7 antibody

GTX55139
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCLCN7
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Overview

  • Supplier
    GeneTex
  • Product Name
    CLCN7 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. ICC/IF: 1:100 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1186
  • Target name
    CLCN7
  • Target description
    chloride voltage-gated channel 7
  • Target synonyms
    chloride channel 7 alpha subunit; chloride channel protein 7; chloride channel, voltage-sensitive 7; CLC7; CLC-7; H(+)/Cl(-) exchange transporter 7; HOD; OPTA2; OPTB4; PPP1R63; protein phosphatase 1, regulatory subunit 63
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP51798
  • Protein Name
    H(+)/Cl(-) exchange transporter 7
  • Scientific Description
    The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • H(+)/Cl(-) exchange transporter 7 promotes lysosomal acidification-mediated autophagy in mouse cardiomyocytes. Lin J et al., 2021 Mar, Mol Med Rep
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