ICC/IF analysis of NIH-3T3 cells using GTX00744 CLGN antibody. Dilution : 1:100 Fixation : 4% PFA, overnight Permeabilization : 0.25% Triton X-100 in PBS for 10 min
CLGN antibody - KO/KD, Orthogonal Validated
GTX00744
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse
TargetClgn
Overview
- SupplierGeneTex
- Product NameCLGN antibody - KO/KD, Orthogonal Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID12745
- Target nameClgn
- Target descriptioncalmegin
- Target synonyms4930459O04Rik; A2/; A2/6; AI528775; C; calmegin; calne; calnexin-T; Cln; MEG 1 antigen
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene belongs to the calreticulin family, which includes calreticulin, calnexin, and calmegin, and encodes a calcium-binding molecular chaperone specifically expressed in pachytene stage male germ cells. It is required for the proper folding of newly synthesized membrane proteins in the endoplasmic reticulum including those critical for sperm migration from the uterus into the oviduct and sperm adhesion to and penetration of the zona pellucida. This gene plays a key role in spermatogenesis and male infertility. Alternative splice variants exist for this gene. [provided by RefSeq, Jul 2016]
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203