CLK1-IN-3 [2922550-28-3]

TargetMol Chemicals

CLK1-IN-3 [2922550-28-3]

9

Chemical

Research Use Only

CLK1-IN-3

99.79%

C24H23FN6O

430.48

Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 42 and 108 nM, respectively. CLK1-IN-3 is effective in inducing autophagy in vitro and can be used for prevention and human treatment of acute liver injury (ALI).

3 years

O=C(NC=1C=NC=2NC=C(C=3C=NC=C(F)C3)C2C1)C4=CC=C(C=C4)N5CCN(C)CC5

-20°C

51202000