(+/-)-Clopidogrel (hydrochloride) [130209-90-4]

TargetMol Chemicals

(+/-)-Clopidogrel (hydrochloride) [130209-90-4]

16

Chemical

Research Use Only

(±)-Clopidogrel (hydrochloride)

C16H17Cl2NO2S

358.28

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix , clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.

3 years

Cl.O=C(OC)C(C=1C=CC=CC1Cl)N2CC=3C=CSC3CC2

-20°C

12352200