CMKLR1 Polyclonal Antibody

Reddot Biotech

CMKLR1 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

CMKLR1

chemerin chemokine-like receptor 1

chemerin receptor; CHEMERINR; chemokine receptor-like 1; chemokine-like receptor 1; ChemR23; DEZ; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ; orphan G-protein coupled receptor, Dez; resolvin E1 receptor; RVER1

Rabbit

IgG

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Human, Mouse

-20°C

12352203