CMP3a [2225902-88-3]

TargetMol Chemicals

CMP3a [2225902-88-3]

86

Chemical

Research Use Only

CMP3a

C28H27F3N6O2S

568.61

CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

3 years

O([C@@H](C)C1=C(C(F)(F)F)C=CC=C1)C=2C=C(C=3N4C(=NC3)C=C(C=C4)C5=CN(CCN(C)C)N=C5)SC2C(N)=O

-20°C

12352200