CMPD101 (hydrochloride)

MedChem Express

CMPD101 (hydrochloride)

5

Research Use Only

C24H22ClF3N6O

502.92

CMPD101 hydrochloride is a novel membrane-permeable, small-molecule inhibitor of both GRK2 and GRK3 with IC 50 s of 18 nM and 5.4 nM, respectively. CMPD101 hydrochloride also inhibits Rho-associated kinase 2 ( ROCK-2 ) and PKCalpha ( IC 50 s =1.4 microM and 8.1 microM, respectively) [1] .

O=C(C1=CC(NCC2=NN=C(C3=CC=NC=C3)N2C)=CC=C1)NCC4=CC=CC=C4C(F)(F)F.[H]Cl

12352200