CMPI hydrochloride

TargetMol Chemicals

CMPI hydrochloride

999

Chemical

Research Use Only

CMPI hydrochloride

Potent positive allosteric modulator of alpha4beta2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for halpha4beta2 over halpha3beta2, halpha3beta4 and halpha7. Inhibits (alpha4)2(beta2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 microM, respectively), but not (alpha4)3(beta2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains.

3 years

-20°C

12352200