CMS-121

MedChem Express

CMS-121 [1353224-53-9]

10

1353224-53-9

Research Use Only

99.63

C20H19NO3

321.37

CMS-121 is a quinolone derivative and an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage with EC 50 values of 7 nM and 200 nM, respectively. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidative and renoprotective activities [1] [2] [3] .

OC1=CC=C(C2=NC3=CC=CC=C3C(OC4CCCC4)=C2)C=C1O

-20°C,2°C to 8°C

12352200