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Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CNOT7 antibody.

CNOT7 Antibody

CSB-PA446150
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetCNOT7
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Overview

  • Supplier
    Cusabio
  • Product Name
    CNOT7 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID29883
  • Target name
    CNOT7
  • Target description
    CCR4-NOT transcription complex subunit 7
  • Target synonyms
    BTG1-binding factor 1; CAF1; CAF-1; Caf1a; carbon catabolite repressor protein (CCR4)-associative factor 1; CCR4-associated factor 1; CCR4-NOT transcription complex subunit 7; hCAF-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UIV1
  • Protein Name
    CCR4-NOT transcription complex subunit 7
  • Scientific Description
    Has 3-5 poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. Bogdan J.A., Biochem. J. 336:471-481(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004).
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203