CNX-774 [1202759-32-7]
ORB181026
CAS Number1202759-32-7
Product group Chemicals
Molecular Weight499.49638
Overview
- SupplierBiorbyt
- Product NameCNX-774 [1202759-32-7]
- Delivery Days Customer16
- CAS Number1202759-32-7
- CertificationResearch Use Only
- Molecular FormulaC26H22N7O3F
- Molecular Weight499.49638
- Scientific DescriptionCNX-774 is a potent, selective, and orally available small molecule inhibitor of Btk (IC50< 1 nM) that forms a ligand-directed covalent bond with Cys-481, a non-conserved amino acid within the active site of the enzyme.
- SMILESO=C(NC)C1=NC=CC(OC2=CC=C(NC3=NC=C(F)C(NC4=CC=CC(NC(C=C)=O)=C4)=N3)C=C2)=C1
- UNSPSC12352200