Cobimetinib (GDC-0973) [934660-93-2]

Selleck Chemicals

Cobimetinib (GDC-0973) [934660-93-2]

9

Research Use Only

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.

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