ICC/IF analysis of methanol-fixed HeLa cells using GTX50199 Cofilin 1 (phospho Ser3) antibody.
ICC/IF analysis of methanol-fixed HeLa cells using GTX50199 Cofilin 1 (phospho Ser3) antibody.
Cofilin 1 (phospho Ser3) antibody
GTX50199
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCFL1
Overview
- SupplierGeneTex
- Product NameCofilin 1 (phospho Ser3) antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. ICC/IF: 1:100-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID1072
- Target nameCFL1
- Target descriptioncofilin 1
- Target synonyms18 kDa phosphoprotein; CFL; cofilin; cofilin 1 (non-muscle); cofilin-1; epididymis secretory protein Li 15; HEL-S-15; p18
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDP23528
- Protein NameCofilin-1
- Scientific DescriptionThe protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- PLD2 regulates microtubule stability and spindle migration in mouse oocytes during meiotic division. Liu X et al., 2017, PeerJRead more