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ICC/IF analysis of methanol-fixed HeLa cells using GTX50199 Cofilin 1 (phospho Ser3) antibody.
ICC/IF analysis of methanol-fixed HeLa cells using GTX50199 Cofilin 1 (phospho Ser3) antibody.
ICC/IF analysis of methanol-fixed HeLa cells using GTX50199 Cofilin 1 (phospho Ser3) antibody.

Cofilin 1 (phospho Ser3) antibody

GTX50199
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCFL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cofilin 1 (phospho Ser3) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:1000. ICC/IF: 1:100-1:200. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1072
  • Target name
    CFL1
  • Target description
    cofilin 1
  • Target synonyms
    CFL, HEL-S-15, cofilin, cofilin-1, 18 kDa phosphoprotein, cofilin 1 (non-muscle), epididymis secretory protein Li 15, p18
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP23528
  • Protein Name
    Cofilin-1
  • Scientific Description
    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Liu X, Chen D, et al. PLD2 regulates microtubule stability and spindle migration in mouse oocytes during meiotic division. PeerJ. 2017,5:e3295. doi: 10.7717/peerj.3295
    Read this paper

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