Coibamide A [1029227-48-2]

TargetMol Chemicals

Coibamide A [1029227-48-2]

999

Chemical

Research Use Only

Coibamide A

C65H110N10O16

1287.63

Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, exhibits potent antiproliferative activity, induces autophagosome accumulation via an mTOR-independent mechanism, and triggers apoptosis. Furthermore, it inhibits VEGFA/VEGFR2 expression, effectively suppressing tumor growth in glioblastoma xenografts [1] [2].

3 years

[H][C@@]1([C@@H](C)CC)N(C)C(=O)[C@H](COC)N(C)C(=O)[C@H]([C@@H](C)OC(=O)[C@@H](C)N(C)C(=O)[C@H](Cc2ccc(OC)cc2)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)NC1=O)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](COC)N(C)C(=O)[C@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C

-20°C

12352200