
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA199023(COL18A1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
COL18A1 Antibody
CSB-PA199023
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCOL18A1
Overview
- SupplierCusabio
- Product NameCOL18A1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID80781
- Target nameCOL18A1
- Target descriptioncollagen type XVIII alpha 1 chain
- Target synonymsantiangiogenic agent; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; endostatin; GLCC; KNO; KNO1; KS; multi-functional protein MFP
- HostRabbit
- IsotypeIgG
- Protein IDP39060
- Protein NameCollagen alpha-1(XVIII) chain
- Scientific DescriptionThis gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203