COL18A1 Polyclonal Antibody

Reddot Biotech

COL18A1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

COL18A1

collagen type XVIII alpha 1 chain

antiangiogenic agent; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; endostatin; GLCC; KNO; KNO1; KS; multi-functional protein MFP

Rabbit

IgG

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human, Mouse

-20°C

12352203