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Collagen II antibody

GTX44077
GeneTex
ApplicationsELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse
TargetCol2a1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Collagen II antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Cross-reactivity (RIA% ):Mouse Collagen Type II 100% Mouse Collagen Type I, III, IV <0.1% Mouse Fibronectin <0.1%
  • Application Supplier Note
    IHC-P: 1:1,000. IHC-Fr: 1:80. ELISA: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID12824
  • Target name
    Col2a1
  • Target description
    collagen, type II, alpha 1
  • Target synonyms
    alpha-1 type II collagen; chondrocalcin; Co; Col2; Col2a; Col2a-1; collagen alpha-1(II) chain; Del; Del1; Dmm; L; Lpk; M100413; procollagen, type II, alpha 1; Rgsc4; Rgsc413; Rgsc8; Rgsc856
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP28481
  • Protein Name
    Collagen alpha-1(II) chain
  • Scientific Description
    This gene encodes the alpha-1 subunit of the fibril-forming type II collagen, the major component of cartilage and the vitreous humor of the eye. The encoded preproprotein forms homotrimeric, triple helical procollagen that undergoes proteolytic processing during fibirl formation. Mice harboring certain mutations in this gene exhibit severe chondrodysplasia characterized by short limbs and trunch, craniofacial deformities and cleft palate. A complete lack of the encoded protein in mice results in postnatal lethality. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Dec 2015]
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203