Compound 112254 . hydrochloride (water soluble) [949745-75-9]

Name: Compound 112254 . hydrochloride (water soluble) [949745-75-9]
SKU: AG-CR1-0157_A27
Price: 94 EUR
Availability: BackOrder

AG-CR1-0157

CAS Number949745-75-9

Product group Chemicals

Estimated Purity>98%

Molecular Weight437.6 . 36.5 . 18.0

Overview

Supplier
AdipoGen Life Sciences
Product Name
Compound 112254 . hydrochloride (water soluble) [949745-75-9]
Delivery Days Customer
10
CAS Number
949745-75-9
Certification
Research Use Only
Estimated Purity
>98%
Molecular Formula
C26H35N3O3 . HCl . H2O
Molecular Weight
437.6 . 36.5 . 18.0
Scientific Description
Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Prod. No. AG-CR1-0154) http://www.adipogen.com/ag-cr1-0154/adiporon.html [1, 2]. Activates 5-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1]. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1]. - Chemical. CAS: 949745-75-9 (free base). Formula: C26H35N3O3 . HCl . H2O. MW: 437.6 . 36.5 . 18.0. Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Prod. No. AG-CR1-0154) http://www.adipogen.com/ag-cr1-0154/adiporon.html . Activates 5-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms.
SMILES
[Cl-].COC1=CC=C(C[NH+]2CCN(CC2)C(=O)CCNC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity: M. Okada-Iwabu, et al.; Nature 503, 493 (2013)
Cell Biology. Ronning after the adiponectin receptors: W.L. Holland & P.E. Scherer; Science 342, 1460 (2013)